Multiple choice

Triptans are used for the treatment of migraine and they act through

  1. 5HT-1A

  2. 5HT-1B

  3. 5HT-1F

  4. 5HT-3

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Triptans like sumatriptan are selective 5-HT1B/1D receptor agonists. They cause cranial vasoconstriction and inhibit trigeminal nerve release of neuropeptides, effectively aborting migraine attacks. They do not act significantly on 5HT-1A, 5HT-1F, or 5HT-3 receptors.