Multiple choice

Blocking of acetylcholine receptors at the postsynaptic neuromuscular junction by circulating antibodies causes

  1. myasthenia gravis

  2. polymyalgia rheumatica

  3. microscopic polyangiitis

  4. Behcet's syndrome
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A Correct answer
Explanation

Myasthenia gravis or muscle weakness is caused by circulating antibodies that block acetylcholine receptors at the postsynaptic neuromuscular junction. It inhibits the excitatory effects of neurotransmitter acetylcholine on nicotinic receptors at neuromuscular junctions.

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