Multiple choice

Which among the whole-genome sequencing methods has the capability to target multiple genes simultaneously?

  1. Polymerase chain reaction

  2. Molecular inversion probe

  3. Hybrid capture

  4. In-solution capture

  5. Sequencing
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A Correct answer
Explanation

Polymerase chain reaction (PCR) is a technology to amplify specific DNA sequences. It uses a single stranded piece of DNA as a start for DNA amplification. Uniplex PCR uses only one starting point (primer) for amplification and multiplex PCR uses multiple primers. This way multiple genes can be targeted simultaneously.

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