Multiple choice

Which among the following methods of sequencing DNA produces information about both identity and location of nucleotide sequences within the genome of an individual?

  1. Transposon sequencing

  2. Deep sequencing

  3. Exome sequencing

  4. Positional sequencing

  5. MicroRNA sequencing
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D Correct answer
Explanation

Positional sequencing is a method of sequencing DNA that simultaneously generates information about both identity and location of nucleotide sequences. The method involves detecting the location of sequence specific recognition events (e.g., such as hybridization of probes of known sequence) on single DNA molecules.

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