Multiple choice

Which of the following characterises an oncogene?

  1. It is a predominantly expressed mutation providing growth or survival advantage to the cell.

  2. It codes for a mutated form of a protein which creates fractions of a signal transduction pathway.

  3. It codes for a protein which restricts the cell from apoptosis.

  4. It codes for a specific protein, which controls cell cycle in a cell.
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A Correct answer
Explanation

An oncogene is a mutated form of a normal cellular gene (the proto-oncogene) which codes for a protein which is either controlled abnormally so that it is expressed in abnormally large amounts or has gained activity so that it is more active than the normal protein.

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