Multiple choice

Which of the following compound stabilize C3 convertase in this alternative pathway?

The alternative pathway of complement activation is triggered when a breakdown product of C3 hydrolysis, C3b is deposited on the surface of a microbe. Next step in this pathway is to form C3 convertase which enzymatically breaks down more C3.

  1. Factor D

  2. Properdin

  3. Histamine

  4. Cytokine

  5. Integrin
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Properdine stabilizes the C3 convertase on microbial surface.

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