Multiple choice

Which of the following characterises an oncogene?

  1. In tumor cells, they are expressed at lower levels.

  2. It codes for a cell cycle control protein in a cell.

  3. It codes for a protein, which restricts the cell from apoptosis.

  4. It codes for a mutated form of a protein which creates fractions of a signal transduction pathway.

  5. It is a predominantly expressed mutation, which provides growth or survival advantage to a cell.
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E Correct answer
Explanation

An oncogene is a mutated form of a normal cellular gene (the proto-oncogene) that codes for a protein, which is either controlled abnormally, so that it is expressed in abnormally large amounts or has gained activity. It is more active than the normal protein.

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