Multiple choice

Which among the following oncogenes forms the death-inducing signalling complex in humans?

  1. pVHL

  2. APC

  3. Fas

  4. YPEL3

  5. ST14

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Fas forms the death-inducing signaling complex (DISC) upon ligand binding. Membrane-anchored Fas ligand trimer on the surface of an adjacent cell causes oligomerization of Fas.