Multiple choice

Which among the following statements characterises an oncogene?

  1. It codes for a cell cycle control protein in a cell.

  2. It codes for a protein which restricts the cell from apoptosis.

  3. It codes for a mutated form of a protein which creates fractions of a signal transduction pathway.

  4. Many cancer drugs target the proteins encoded by oncogenes.

  5. It is a predominantly expressed mutation providing a cell a growth or survival advantage.
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E Correct answer
Explanation

An oncogene is a mutated form of a normal cellular gene (the proto-oncogene) which codes for a protein which is either controlled abnormally so that it is expressed in abnormally large amounts or has gained activity so that it is more active than the normal protein.

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