Multiple choice

The genetic disorder sickle-cell anemia signifies

  1. mutation

  2. pleiotropy

  3. epistasis

  4. heterozygous dominance
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A Correct answer
Explanation

The sickle cell is an example of a mutation that is beneficial when maintained in heterozygotes. When you are homozygous for the trait you get sickle cell anemia. When a person is heterozygous for the sickle cell gene they have some added protection from malaria.

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