Multiple choice

Niemann-Pick disease is a group of inherited severe metabolic disorders in which sphingomyelin accumulates in lysosomes in cells. Which of the following nerve cells are progressively lost in this condition?

  1. Betz cells

  2. Basket cells

  3. Purkinje cells

  4. Lugaro cells

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Niemann-Pick disease type C involves the progressive loss of Purkinje cells. In this disease, sphingomyelin accumulates in lysosomes in the cells.