Multiple choice

In Lysosomal Storage Disorders, which of the following is true?

  1. The lysosomes are deficient in the enzyme hydrolase.

  2. There is a defect in the fusion of lysosomes and phagosomes.

  3. There is a defect in the lysosomal membrane.

  4. None of these

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Lysosomal Storage Disorders are characterized by deficiency of specific lysosomal hydrolase enzymes, leading to accumulation of substrates within lysosomes. The primary defect is the absence or dysfunction of these hydrolytic enzymes. Options B and C describe other possible lysosomal dysfunctions but are not the defining feature of LSDs. Option D is incorrect because the enzyme deficiency (Option A) is the hallmark of these disorders.