Multiple choice

In Lysosomal Storage Disorders, true is:

  1. The lysosomes are deficient in the enzyme hydrolase

  2. There is a defect in the fusion od lysosomes and phagosomes

  3. There is a defect in the lysosomal membrane

  4. None of these

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A Correct answer
Explanation

Lysosomal storage disorders are caused by deficiency of specific hydrolytic enzymes within lysosomes. This leads to accumulation of substrates that would normally be degraded. The primary defect is not in lysosomal membrane structure or fusion with phagosomes - the core issue is missing or deficient hydrolase enzymes.