Multiple choice

A multifactorial trait occurs more often in females than males. A couple have an affected son. Which of the following is true regarding their risk of recurrence?

  1. Recurrence is higher if they had an affected daughter, and is most likely for a future son.

  2. Recurrence is higher if they had an affected daughter, and is most likely for a future daughter.

  3. Recurrence is lower if they had an affected daughter, and is most likely for a future son.

  4. Recurrence is lower if they had an affected daughter, and is most likely for a future daughter.

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Since females are more often affected, having an affected son implies greater liability towards the trait. This increases their risk for future offspring. The trait will always be more common in females than males.