Tag: blood clotting and healing of wounds

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Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Which one of the following substances, if introduced in blood stream would cause coagulation of blood at the site of its introduction?

  1. Prothrombin

  2. Fibrinogen

  3. Thromboplastin

  4. Heparin.
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Thromboplastin is the initiator of the extrinsic clotting pathway; introducing it directly into the bloodstream triggers the coagulation cascade at that site.

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Find the correct explanations about blood not clotting inside the vessels
1. Speedy flow prevents accumulation of fibrin threads if formed
2. Absence of anticoagulant heparin having antithrombin activity
3. Smoothness of endothelial lining preventing rupturing of platelets and formation of thromboplastin
4. Presence of a layer of negetively charged protein over the inner surface of endothelium that attracts clotting factors.

  1. 1, 2, 3 correct

  2. 1, 2 correct

  3. 2, 4 correct

  4. 1, 3 correct.
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Blood does not clot inside vessels due to the smooth endothelial lining (preventing platelet rupture) and the rapid flow of blood (preventing the accumulation of clotting factors). Heparin is present as a natural anticoagulant, and the endothelium is negatively charged to repel platelets.

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Identify the correct sequence of blood coagulation (a) Activation of prothrombin (b) Formation of prothrombin activator (c) Formation of blood clot (d) Conversion of fibrinogen to fibrin

  1. b - d - a - c

  2. b - a - d - c

  3. a - d - c - b

  4. a - b - c - d
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation
Blood coagulation occurs in the following sequence:
  • Whenever there is rupture of blood vessels or damage is caused to blood, a complex of substances called prothrombin activator complex is formed. 
  • The activators convert prothrombin into thrombin.
  • Thrombin acts as an enzyme and converts fibrinogen into fibrin threads.
  • Fibrin threads accumulate and clump to form blood clot at the wound site.
So, the correct answer is 'b- a- d- c'.
Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

The factor which initiates intrinsic pathway of blood clotting and triggers cascade reaction is

  1. Antihaemophiliac factor (VIII)

  2. Christmas factor (IX)

  3. Stuart-Prower factor (X)

  4. Hageman's factor (XII).
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Hageman's factor (Factor XII) is the contact activation factor that initiates the intrinsic pathway of the blood coagulation cascade when it comes into contact with exposed collagen or other negatively charged surfaces.

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Thrombokinase is associated with

  1. Elimination of area and other excretory products from the body

  2. Production of erythrocytes from the bone marrow

  3. Pulmonary and systemic circulation

  4. Cardiac cycle and its regulation

  5. Enzymatic reactions in coagulation of blood.
Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Thrombokinase (also known as thromboplastin) is an enzyme that plays a critical role in the coagulation cascade by converting prothrombin into thrombin. This process is essential for blood clotting.

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Thrombokinase is associated with

  1. Ellimination of urea and other excreatory products from the body.

  2. Production of erythrocytes from the bone marrow.

  3. Pulmonary and systematic circulation.

  4. Cardiac cycle and its regulation

  5. Enzymatic reactions in coagulation of blood.
Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Thrombokinase is a substance present in platelets which are necessary for coagulation of blood. Thromboplastin helps in the conversion of prothrombin to thrombin in the presence of calcium which is the vital step in coagulation of blood.

Hence, the correct option is E.