Tag: blood clotting and healing of wounds

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Questions Related to blood clotting and healing of wounds

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Which enzyme induces lysis of fibrinogen to fibrin during fibrinolysis?

  1. Plasmin

  2. Thrombin

  3. Fibrin

  4. Trypsin
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Blood-clotting proteins circulate in the blood plasma in an inactive form, poised to participate in blood coagulation upon tissue injury. Blood-clotting proteins generate thrombin, an enzyme that converts fibrinogen to fibrin, and a reaction that leads to the formation of a fibrin clot.

Therefore, the correct answer is option B.

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

In human, the prothrombin required for blood clotting is produced inside the

  1. Liver

  2. Blood

  3. Bone

  4. Spleen
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Prothrombin is a coagulation or clotting factor that is needed for the normal clotting of blood. A cascade of biochemical events leads to the formation of the final clot. In this cascade, prothrombin is a precursor to thrombin.
Prothrombin is produced in the liver and is modified in the presence of vitamin K.
Therefore, the correct answer is option A.

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Which of the following happens if platelets are absent in blood?

  1. Severe bleeding in case of injury or cuts

  2. Body cannot form clots

  3. Thrombocytopenia

  4. All of the above
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Platelets are components of blood. They prevent bleeding by activating coagulation mechanisms hence contribute in wound healing. They play an important role in inflammatory and proliferative events. If the platelets are not present in the blood there will be continuous loss of blood by the blood vessels which may prove fatal.

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Blood clotting can be prevented in a test tube by adding a little

  1. Sodium oxalate

  2. Sodium chloride

  3. Sodium hydroxide

  4. Ammonium chloride
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Sodium oxalate acts as an anticoagulant. Sodium oxalate inhibits blood coagulation by forming an insoluble complex with calcium because calcium is a cofactor that involves in the clotting process. Hence, option A is the correct answer.

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Blood does not clot inside the blood vessels due to the presence of

  1. Heparin

  2. Fibrinogen

  3. Vitamin K

  4. Thrombin
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation
Liver produces an anticoagulant, hetero-polysaccharide called heparin which prevent clotting inside the blood vessels. Heparin is a highly sulfated glycosaminoglycan and is also used to form an inner anticoagulant surface on experimental and medical devices.
Fibrinogen is a glycoprotein that helps in the formation of blood clots.
Thrombin is a blood coagulation factor.
Thus, the correct answer is option A. 
Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Which of the following does not play a role in blood coagulation?

  1. Vitamin K

  2. Vitamin D

  3. Calcium ions

  4. Fibrinogen
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Fibrinogen is factor I and its source is liver. When fibrinogen is converted into fibrin by thrombin, it forms long strands, that compose the mesh network for clot formation.
Calcium is factor IV and its source is bone and absorption from food in gastrointestinal tract. It works with many clotting factors for activation of the other clotting factors.
Vitamin K is an essential factor to various protein enzymes, that are a part of coagulation cascade.
Vitamin D is found in fish and liver oil and is essential for absorption of calcium.
Thus, the correct answer is option B.

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

A drop of each of the following, is placed separately on four slides. Which of them will not coagulate?

  1. Blood plasma

  2. Blood serum

  3. Sample from the thoracic duct of lymphatic system

  4. Whole blood from pulmonary vein
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Coagulation is the process by which the blood changes from a liquid to a gel-like form. Blood plasma will coagulate, as, it has clotting factors in it and fibrinogen protein.
Serum will not coagulate, as, it do not have any clotting factors and fibrinogen.
Lymph is more like blood plasma, so, contains clotting factors and will coagulate.
Whole blood obviously coagulate for containing the same above factors.
Thus, the correct answer is option (B).

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Which of the following protein is responsible for spontaneous blood clotting?

  1. Factor XII

  2. Factor XI

  3. Factor IX

  4. Factor VIII
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Factor VIII is an important blood clotting protein, which is also known as anti-haemophilic factor (AHF), encoded by the F$ _{8}$ gene.
Factor VIII circulates in the bloodstream in an inactive form, bound to another molecule, called Von Willebrand factor, until an injury that damages the blood vessels occurs. When injury occurs, the factor VIII is activated and separates from Von Willebrand factor. The active protein interacts with another coagulation factor, called factor IX. This interaction leads to a chain of additional reactions, that form a blood clot.

Multiple choice biology soldiers of defense blood clotting and healing of wounds coagulation of blood blood clotting

Which of the following are required for blood clotting?

  1. K${^+}$, thromboplastin
  2. Ca${^+}$${^+}$, thromboplastin
  3. Na${^+}$, Ca${^+}$${^+}$
  4. K${^+}$, prothrombin
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

When there is an injury and blood is shed, the platelets disintegrate and liberate thromboplastin or factor III. Certain amount of thromboplastin is also derived from the damaged tissues of the injured locality.
Thromboplastin converts prothrombin into thrombin with the help of calcium ions and thrombin interacts with fibrinogen forming fibrin. This is clot.
Calcium is the Factor IV and it acts as a co-factor in the coagulation process.
Thus, the correct answer is option (B).