Tag: active and passive immunity

Questions Related to active and passive immunity

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Grafted kidney may be rejected in a patient due to 

  1. Humoral immune system

  2. Cell mediated immune response

  3. Passive immune response

  4. Innate immune response

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation
  • The grafted kidney may be rejected in a patient due to the cell-mediated immune response that is mediated by T-lymphocytes.
  •  The body is able to differentiate 'self' and 'non-self'. 
  • Therefore, tissue matching, blood group matching are essential before undertaking any graft/transplant and even after this the patient has to take immunosuppressants all his/her life.
  •  Hence, the Grafted kidney may be rejected in a patient due to Cell-mediated immune response.
  • So, the correct answer is 'Cell-mediated immune response'.
Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Read the following statement having two blanks (A and B). "A drug used for A patients is obtained from a species of the organism B. The one correct option for the two blanks is

  1. A-heart, B-Penicillium

  2. A-organ-transplant, B-Trichoderma

  3. A-swine flu, B-Monascus

  4. A-AIDS, B-Pseudomonas

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

A) $Penicillium$ is an antibiotic and is not related to heart patients.
B) $Trichoderma\quad polysporum$ is a fungus that is used to produce the drug cyclosporine which is used to overcome rejection reactions after organ translplants.
C) $Monascus\quad purpureus$ is a yeast from which statins are produced which acts as a clot buster and controls cholesterol levels. It is not related to swine flu.

D) $Pseudomonas$ is an infection causing bacteria. AIDS is caused by a virus.
So the correct answer is 'A-organ-transplant, B-Trichoderma'.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Major histocompatibility (MHC) complex genes are present in which of the following chromosome of humans?

  1. Chromosome 22

  2. Chromosome 7

  3. Chromosome 6

  4. X chromosome

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

A group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances Major histocompatibility (MHC) complex genes. In vertebrates, the major histocompatibility complex (MHC) genes present on chromosome 6 code for a set of cell surface proteins that are  essential for the acquired immune system to recognize foreign molecules, which determines histocompatibility.

So, the correct  option is 'chromosome 6'.
Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Which of the following drugs is used in leukaemia patients as an immunosuppressant?

  1. Cyclophosphamide

  2. Tetracycline

  3. Beta blockers

  4. None of the above

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

A-Cyclophosphamide CP known as cytophoshphane among other names is a medication used as chemotherapy and to suppress the immune system. Chemotherapy is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma.

So the correct option is A.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Azathioprine is given before and after organ transplant because

  1. It inhibits mitosis.

  2. It decreases T and B cell proliferation.

  3. It inhibits meiosis.

  4. Both A and B.

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Azathioprine is a purine analogue that interferes with DNA synthesis, thereby inhibiting mitosis and the proliferation of T and B cells. Since both A and B describe the mechanism of action, D is the correct choice.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

 ............. are fungal metabolites with immunosuppressive properties.

  1. Cyclosporin A

  2. Rapamycin

  3. Tetracycline

  4. Both A and B

Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Both Cyclosporin A (derived from Tolypocladium inflatum) and Rapamycin (derived from Streptomyces hygroscopicus) are well-known fungal metabolites used as potent immunosuppressants in transplantation.

Multiple choice zoology immune system active and passive immunity immunity related disorders and problems diseases and immunity

Cyclosporin is useful in

  1. Prophylactic for viruses

  2. Immunosuppressant

  3. Prophylactic for marasmus

  4. Treating allergic eozema

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Cyclosporin is an effective immunosuppressant used in the treatment of autoimmune disorders (such as rheumatoid arthritis) and in organ transplantation to prevent rejection. Cyclosporin lowers the activity of T-cells and hence, suppressing the activity of the immune system. Cyclosporin was isolated from the fungus Tolypocladium inflatum. Common side effects include high blood pressure, headache, kidney problems, increased hair growth, and vomiting. So, the correct answer is 'Immunosuppressant'.