Tag: genome projects

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Multiple choice zoology molecular basis of inheritance genome projects human genome project human genome project and dna fingerprinting

All of the following except are sources of change in the genome

  1. Nondisjunction during meiosis

  2. Gene mutations

  3. Crossing over

  4. Amniocentesis
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

A process in which amniotic fluid is sampled using a hollow needle inserted into the uterus, to screen for abnormalities in the developing fetus.

It is not part of the change in a genome, so the correct answer is D, amniocentesis.

Multiple choice zoology molecular basis of inheritance genome projects human genome project human genome project and dna fingerprinting

The human genome project involves all of the following except

  1. altering the human genome

  2. physical mapping of the chromosomes

  3. sequencing of the entire nucleotide sequence of the human genome

  4. location of RFLP markers
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation
The Human Genome Project (HGP) was launched on 1st October 1990 for sequencing the entire genome of 2.75 billion nucleotide pairs. This megaproject was a 13-year project coordinated by the U.S. Department of Energy and the National Institute of Health. During the early years of the HGP, the Wellcome Trust (U.K.) becomes a major partner; additional contributions come from Japan, France, Germany, China, and others. The project was completed in 2003. This project had the following objectives:-
  • To identify all the approximately 20,000-25,000 genes in human DNA.
  • To determine the sequences of the 3 billion base pairs that make up human DNA. 
  • Knowing locations of RFLP markers. Restriction fragment length polymorphism (RFLP) is a technique that exploits variations in homologous DNA sequences. The principle of RFLP markers is that any genomic DNA can be differentiated according to the presence or absence of restriction enzyme sites. 
  • Mapping presence of genes on different chromosomes. 
So, the correct option is 'altering the human genome'.
Multiple choice zoology molecular basis of inheritance genome projects human genome project human genome project and dna fingerprinting

The sequencing of the entire genome (the totality of all genes) of an organism was completed in 1996. The organism was

  1. Human being

  2. Yeast

  3. Albino mouse

  4. Plasmodium vivax
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

The sequencing of the entire genome of an organism was completed in 1996 and the organism was yeast.

So, the correct option is 'Yeast'.

Multiple choice zoology molecular basis of inheritance genome projects human genome project human genome project and dna fingerprinting

Human Genome Project is under the control of Human Genome Organization which is funded primarily by

  1. NIH in USA

  2. DOE in USA

  3. EC in Europe

  4. All of the above
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

The Human Genome Project (HGP) is an international scientific research project with the goal of determining the sequence of chemical base pairs which make up human DNA and of identifying and mapping all of the genes of the human genome from both a physical and functional standpoint. It remains the world's largest collaborative biological project. The project was proposed and funded by the US government; planning started in 1984, the project got underway in 1990 and was declared complete in 2003. The project has been organized and supported primarily by the DOE, European Commission and the NIH, which established working groups to address genome mapping, computational analysis to handle databases, and the social, legal, and ethical implications of the human genome research. Congress funds the project through the National Centre for Human Genome Research at the NIH, which in turn awards grants and contracts to U.S. investigators. Additional funding from Congress goes to the DOE, which conducts research on human genetics at three national laboratories and also funds independent or private investigators.

Multiple choice zoology mutation genome projects human genome project human genome project and dna fingerprinting

Human genome project was discovered by

  1. Francis Collins and Roderick

  2. Watson and Crick

  3. Beadle and Tatum

  4. Paul Berg and Wollman
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

The Human Genome Project was a massive international research effort, and Francis Collins served as the director of the NIH's National Human Genome Research Institute during the project.