Tag: immunity related disorders and problems

Questions Related to immunity related disorders and problems

Read the following statement having two blanks (A and B). "A drug used for A patients is obtained from a species of the organism B. The one correct option for the two blanks is

  1. A-heart, B-Penicillium

  2. A-organ-transplant, B-Trichoderma

  3. A-swine flu, B-Monascus

  4. A-AIDS, B-Pseudomonas


Correct Option: B
Explanation:

A) $Penicillium$ is an antibiotic and is not related to heart patients.
B) $Trichoderma\quad polysporum$ is a fungus that is used to produce the drug cyclosporine which is used to overcome rejection reactions after organ translplants.
C) $Monascus\quad purpureus$ is a yeast from which statins are produced which acts as a clot buster and controls cholesterol levels. It is not related to swine flu.

D) $Pseudomonas$ is an infection causing bacteria. AIDS is caused by a virus.
So the correct answer is 'A-organ-transplant, B-Trichoderma'.

Major histocompatibility (MHC) complex genes are present in which of the following chromosome of humans?

  1. Chromosome 22

  2. Chromosome 7

  3. Chromosome 6

  4. X chromosome


Correct Option: C
Explanation:

A group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances Major histocompatibility (MHC) complex genes. In vertebrates, the major histocompatibility complex (MHC) genes present on chromosome 6 code for a set of cell surface proteins that are  essential for the acquired immune system to recognize foreign molecules, which determines histocompatibility.

So, the correct  option is 'chromosome 6'.

Which of the following drugs is used in leukaemia patients as an immunosuppressant?

  1. Cyclophosphamide

  2. Tetracycline

  3. Beta blockers

  4. None of the above


Correct Option: A
Explanation:

A-Cyclophosphamide CP known as cytophoshphane among other names is a medication used as chemotherapy and to suppress the immune system. Chemotherapy is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma.

So the correct option is A.

Azathioprine is given before and after organ transplant because

  1. It inhibits mitosis.

  2. It decreases T and B cell proliferation.

  3. It inhibits meiosis.

  4. Both A and B.


Correct Option: D

 ............. are fungal metabolites with immunosuppressive properties.

  1. Cyclosporin A

  2. Rapamycin

  3. Tetracycline

  4. Both A and B


Correct Option: D

Cyclosporin is useful in

  1. Prophylactic for viruses

  2. Immunosuppressant

  3. Prophylactic for marasmus

  4. Treating allergic eozema


Correct Option: B
Explanation:

Cyclosporin is an effective immunosuppressant used in the treatment of autoimmune disorders (such as rheumatoid arthritis) and in organ transplantation to prevent rejection. Cyclosporin lowers the activity of T-cells and hence, suppressing the activity of the immune system. Cyclosporin was isolated from the fungus Tolypocladium inflatum. Common side effects include high blood pressure, headache, kidney problems, increased hair growth, and vomiting. So, the correct answer is 'Immunosuppressant'.

Choose the correct answer among the alternatives given :


The sexually transmitted disease, that can affect both the male and the female genitals and may damage the eyes of babies born of infected mothers is

  1. AIDS

  2. Syphilis

  3. Gonorrhoea

  4. Hepatitis


Correct Option: C
Explanation:

Gonorrhea is caused by a Diplococcus bacterium. The victim feels a burning sensation during urination. The incubation period is around 25 days. 


The disease affects the inner membrane of the urinogenital tract and spreads by sexual contact. The infection we spread to other parts of the body and causes arthritis and female sterility. 
The children born to affected mothers often suffer from my eye infection. It is also easily curable.
So, the correct option is 'Gonorrhoea'.

Which one of the following statements is correct with respect to AIDS?

  1. Drug addicts are least susceptible to HIV infection

  2. AIDS patients are being fully cured $100\%$ with proper care and nutrition

  3. The causative HIV retrovirus reduces the number of T-helper lymphocytes

  4. HIV can be transmitted through eating food together with an infected person


Correct Option: C
Explanation:

 HIV is a retrovirus that primarily infects components of the human immune system such as CD4+ T cells, macrophages and dendritic cell. It, directly and indirectly, destroys CD4+ T cells.

So, the correct option is 'The causative HIV retrovirus reduces the number of T-helper lymphocytes'.

Choose the correct statement/s.
I. A person suffering from AIDS may die from any disease.
II. When a person suffers from AIDS, then his/her immune system becomes stronger.

  1. Only I

  2. Only II

  3. Both are correct

  4. Both are incorrect


Correct Option: A
Explanation:

Acquired immune deficiency syndrome (AIDS) is a disease caused by HIV in which a person's immunity is badly damaged such that any disease may effect his or her health adversely resulting in appreciable effect on the overall  life expectancy of that person.


Hence, 'Only I' is correct.

Which of the following diseases spreads through infected needles or blood transfusion?

  1. Jaundice

  2. AIDS

  3. Measles

  4. Polio


Correct Option: B
Explanation:

AIDS (Acquired immunodeficiency syndrome) is an infection which is caused by Human immunodeficiency virus (HIV). The causative agent of the disease is a virus and so the disease can spread from one person to the other by sexual contact. The disease alsoe spreads through the use of teh infected needles, syringes and blood transfusion from the infected person.

Thus, the correct answer is option B.