Tag: immunity related disorders and problems

Questions Related to immunity related disorders and problems

Arrange the given statement in the correct order according to type II hypersensitivity reactions.
a) IgG or IgM antibodies react with the antigen on the surface of cells.
b) Opsonization and phagocytosis. 
c) Activation of the complement cascade.
d) Cell death and lysis.

  1. a,b,c,d

  2. a,c,b,d

  3. a,d,c,b

  4. None of the above


Correct Option: B

Tuberculin, a type of hypersensitivity IV was given by ____________

  1. Louis Pasteur.

  2. Alexender Flemming.

  3. Robert Koch.

  4. None of the above.


Correct Option: C

Which of the following cell releases a hydrolytic enzyme during type IV hypersensitivity reaction?

  1. Macrophages

  2. T killer cells

  3. T helper cells

  4. All of the above


Correct Option: A
Explanation:
Type IV hypersensitivity Is a type of cell-mediated response. CD4+ helper T cells recognize antigen in a complex with major histocompatibility complex  Class II. The antigen-presenting cells are macrophages that secrete IL-12, which stimulates the proliferation of further CD4+ Th cells which secrete IL-2 and interferon gamma. This further inducing the release of other Th cytokines, thus mediating the immune response. Activated CD8+ T cells kill target cells on contact, whereas activated macrophages produce hydrolytic enzymes. Thus the correct answer is option A. 

Which of the following step is not a part of hypersensitivity type IV reaction?

  1. Sensitization

  2. Antigen presentation

  3. Phagocytosis

  4. All of the above


Correct Option: D

Hypersensitivity type IV reaction does not involve 

  1. Phagocytosis.

  2. Antibodies.

  3. Lymphokines.

  4. None of the above.


Correct Option: B

Which of the following is released by T cell to activate lymphocytes and phagocytic cells?

  1. Cytokines

  2. Antibodies

  3. Histamine

  4. None of the above


Correct Option: A
Explanation:

The T helper cells also known as CD$ _4^+$ release cytokines and trigger the activity of other immune cells.

So, the correct answer is 'Cytokines'

Which of the following cell first move to the site in type Iv hypersensitivity reaction?

  1. T helper

  2. T killer cell

  3. Monocytes

  4. None of the above


Correct Option: A

The skin prick test generally test the allergy by 

  1. Skin response

  2. Inflammatory reaction

  3. Composition of blood

  4. None of these


Correct Option: B

Which one is allergic disease?

  1. Bronchitis

  2. Bronchial asthma

  3. Emphysema

  4. Pneumonia


Correct Option: B

The skin prick test is used to diagnose

  1. Allergy

  2. Skin response

  3. Skin texture

  4. None of these


Correct Option: A