Tag: endocrine system and chemical co-ordination

Questions Related to endocrine system and chemical co-ordination

The cause of hyperprolactinemia in males may be

  1. Dehydration

  2. Tumors

  3. Excessive intake of salts

  4. None of the above


Correct Option: B
Explanation:

  • Prolactin levels may be elevated for any number of reasons. One of the more common cause is the formation of a benign tumour on the pituitary gland. 
  • This noncancerous growth, known as a prolactinoma, directly secretes excessive prolactin while decreasing the levels of other sex hormones. Hence, The cause of hyperprolactinemia in males may be Tumors
So, the correct answer is 'Tumors'.

Which of the following is responsible for steroid production?

  1. Salt

  2. Lipids

  3. Cholesterol

  4. None of the above


Correct Option: B
Explanation:

  • Cholesterol also plays a role in synthesizing the steroid hormones aldosterone, which is used for osmoregulation, and cortisol, which plays a role in metabolism. 
  • Cholesterol is also the precursor to bile salts, which help in the emulsification of fats and their absorption by cells. Hence,  Lipids is responsible for steroid production.
So, the correct answer is 'Lipids'.

Which of the following is not involved as $2^{nd}$ messenger?

  1. cAMP

  2. DAG

  3. Phospholipase

  4. $IP _{3}$


Correct Option: C

As per accepted concept of hormone action, if receptor molecules are removed from target organs, the target organs will

  1. Continue to respond to hormone but in opposite way

  2. Continue to respond to hormone without any difference

  3. Continue to respond to hormone but will require higher concentration

  4. Stop responding to hormone


Correct Option: D
Explanation:
Hormones bind to specific proteins known as hormone receptors to produce their effects. These receptors are present on target tissues only. There are two types of receptors in target tissues:
  • Membrane bound receptors : These are present on the cell membrane of target cells.
  • Intracellular receptors: These are present inside the target cell.
When a hormone binds to its receptor, hormone receptor complex is formed. This complex leads to some biochemical changes in target tissue. Hormones regulate metabolism and physiological functions of target tissue.
Hence, if receptor molecules are removed from target organs, the target organs will stop responding to hormones.
So, the correct answer is 'Stop responding to hormone'.

Receptors for protein hormones are found

  1. Inside nucleus

  2. Inside cytoplasm

  3. On surface of ER

  4. On the plasma membrane of the cell


Correct Option: D
Explanation:
Protein hormones are peptide hormones which are derived from amino acids. These are insoluble in lipids and hence can't enter the target cell (cell membrane is a lipid bilayer). These act as primary messengers at the surface of target cell by binding to cell surface receptors and this results in the formation of a hormone-receptor complex.
So, the correct answer is 'On the plasma membrane of the cell'.

In hormone action, if receptor molecules are removed from target organ, the target organ will 

  1. Continue to respond to hormone

  2. Not respond to hormone

  3. Continue to respond but requires higher concentration

  4. Continue to respond but in the opposite way


Correct Option: B
Explanation:
Hormones bind to specific proteins known as hormone receptors to produce their effects. These receptors are present on target tissues only. There are two types of receptors in target tissues:
  • Membrane bound receptors : These are present on the cell membrane of target cells.
  • Intracellular receptors: These are present inside the target cell.
When a hormone binds to its receptor, hormone receptor complex is formed. This complex leads to some biochemical changes in target tissue. Hormones regulate metabolism and physiological functions of target tissue.
Hence, if receptor molecules are removed from target organ, the target organ will not respond to hormone.
So, the correct answer is 'Not respond to hormone'.

Steroid hormones, estrogen and testosterone bind to

  1. Membrane ion channels

  2. Enzyme-linked membrane receptors

  3. G-Protein linked membrane receptors

  4. Cytoplasmic receptors


Correct Option: D
Explanation:

Hormones are of 2 types based on their chemical composition. 

  1. Protein hormones: They are build up of amino acids and are soluble in water. 
  2. Steroid hormones: They are build up of fats and are not soluble in water. 
  3. Since the steroid hormones are not soluble in water they can pass through the plasma membrane and bind to the receptors in the cytoplasm.  
So the answer is Cytoplasmic receptors

In heart cells, which one a second messenger that speeds up muscle contraction in response to adrenaline 

  1. cAMP

  2. cGMP

  3. GTP

  4. ATP

  5. AMP


Correct Option: A
Explanation:
Adrenaline binds to its receptors present on the cell surface i.e. plasma membrane. In heart muscles, cAMP (cyclic adenosine monophosphate) acts as a second messenger. It increases muscle contraction in response to adrenaline which is a neurotransmitter secreted from adrenal medulla. cGMP (cyclic guanosine monophosphate) also acts as a second messenger but it decreases muscle contraction in response to acetylcholine.
So, the correct answer is 'cAMP'.

Steroid hormones easily pass through plasma membrane by simple diffusion because they

  1. Are lipid soluble

  2. Are water soluble

  3. Enter through pores

  4. Contain carbon and hydrogen


Correct Option: A
Explanation:

Steroid hormones are made up of fats and they are not soluble in water. They are hydro phobic in nature. Hence they can easily pass through the plasma membrane by simple diffusion. 

So, the answer is 'Are lipid soluble'.