Cytochalasin B is a drug isolated from moulds. It blocks the formation of contractile microfilaments. Which of the following aspects of the cell cycle would be most disrupted due to this ?
Spindle formation is mainly done by centrioles. It helps in separation of chromosomes during cell division. Cytochalasin B is a cell-permeable mycotoxin. It inhibits cytoplasmic division by blocking the formation of contractile microfilaments due to which cell is unable to maintain the desired number of chromosomes and leads to numerical abberations.