Tag: antibody production and vaccination

Questions Related to antibody production and vaccination

Anaphylactic shock is caused due to the release of which of the following hormone?

  1. Adrenalin

  2. Histamine

  3. Glucagon

  4. Somatostatin


Correct Option: B
Explanation:

Histamines are the inflammatory substances which are released by the mast cells and basophils during the allergic reactions. The excessive release of histamine may result in anaphylactic shock. Anaphylaxis is a type of severe allergic reaction which can result in the death of the person. Antihistamines are used for the treatment and cure of the allergic reactions.

Thus, the correct answer is option B. 

Which of the following is required for the cure of anaphylactic shock?

  1. Adrenalin

  2. Antihistamine

  3. Monoclonal antibodies

  4. None of the above


Correct Option: B
Explanation:

Anaphylaxis is a type of severe allergic reaction which can result in the death of the person. The first or the primary treatment which is provided, is that the person is injected with epinephrine which reduces the basic symptoms. Antihistamines are used for the treatment and cure of the allergic reactions. The antihistamines are molecules which are similar in structure to histamine and block the H1 receptors which prevent the release and action of histamines. 

Thus, the correct answer is option B. 

The immunoglobulin involved in the type II hypersensitivity reactions is

  1. IgA.

  2. IgM.

  3. IgG.

  4. Both B and C.


Correct Option: D

Patch test can be related to 

  1. Hypersensitivity I.

  2. Hypersensitivity II.

  3. Hypersensitivity III.

  4. Hypersensitivity IV.


Correct Option: D

Cytotoxic type II reactions are also known as

  1. Hypersensitivity IV.

  2. Hypersensitivity III.

  3. Hypersensitivity II.

  4. Hypersensitivity I.


Correct Option: C

The major type of delayed type hypersensitivity is (are)

  1. Arthus Reaction.

  2. Tuberculin.

  3. Contact dermatitis.

  4. Both B and C.


Correct Option: D

IgE antibodies are known as cytotropic antibodies because

  1. They are fixed on mast cell and basophils.

  2. They are fixed on eosinophils.

  3. They are fixed on neutrophils.

  4. None of the above.


Correct Option: A

Arrange the given statement in the correct order according to type II hypersensitivity reactions.
a) IgG or IgM antibodies react with the antigen on the surface of cells.
b) Opsonization and phagocytosis. 
c) Activation of the complement cascade.
d) Cell death and lysis.

  1. a,b,c,d

  2. a,c,b,d

  3. a,d,c,b

  4. None of the above


Correct Option: B

Tuberculin, a type of hypersensitivity IV was given by ____________

  1. Louis Pasteur.

  2. Alexender Flemming.

  3. Robert Koch.

  4. None of the above.


Correct Option: C

Which of the following cell releases a hydrolytic enzyme during type IV hypersensitivity reaction?

  1. Macrophages

  2. T killer cells

  3. T helper cells

  4. All of the above


Correct Option: A
Explanation:
Type IV hypersensitivity Is a type of cell-mediated response. CD4+ helper T cells recognize antigen in a complex with major histocompatibility complex  Class II. The antigen-presenting cells are macrophages that secrete IL-12, which stimulates the proliferation of further CD4+ Th cells which secrete IL-2 and interferon gamma. This further inducing the release of other Th cytokines, thus mediating the immune response. Activated CD8+ T cells kill target cells on contact, whereas activated macrophages produce hydrolytic enzymes. Thus the correct answer is option A.