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Pharmacology and Therapeutics
1,699 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
Which of the following drugs is known to interact with warfarin?
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Aspirin
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Ibuprofen
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Acetaminophen
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Vitamin K
D
Correct answer
Explanation
Vitamin K is a known antagonist of warfarin, which can reduce its anticoagulant effect.
Which of the following drugs is known to cause QT prolongation?
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Amiodarone
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Quinidine
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Sotalol
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All of the above
D
Correct answer
Explanation
Amiodarone, quinidine, and sotalol are all known to cause QT prolongation, which can increase the risk of torsades de pointes, a potentially fatal heart rhythm disorder.
Which of the following drugs is known to interact with lithium?
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Diuretics
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NSAIDs
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ACE inhibitors
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All of the above
D
Correct answer
Explanation
Diuretics, NSAIDs, and ACE inhibitors can all interact with lithium, increasing the risk of lithium toxicity.
Which of the following drugs is known to interact with alcohol?
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Acetaminophen
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Ibuprofen
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Aspirin
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All of the above
D
Correct answer
Explanation
Acetaminophen, ibuprofen, and aspirin can all interact with alcohol, increasing the risk of liver damage.
Which of the following drugs is known to interact with grapefruit juice?
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Statins
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Calcium channel blockers
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Beta-blockers
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All of the above
D
Correct answer
Explanation
Statins, calcium channel blockers, and beta-blockers can all interact with grapefruit juice, increasing the risk of adverse effects.
Which of the following drugs is known to cause hepatotoxicity?
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Acetaminophen
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Ibuprofen
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Aspirin
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All of the above
A
Correct answer
Explanation
Acetaminophen is the only drug listed that can cause hepatotoxicity, which is a liver condition.
Which of the following drugs is commonly associated with Stevens-Johnson Syndrome?
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Penicillin
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Sulfonamides
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Allopurinol
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Ibuprofen
B
Correct answer
Explanation
Sulfonamides are a group of antibiotics that can cause a severe skin reaction known as Stevens-Johnson Syndrome.
Which of the following drugs is commonly associated with hepatotoxicity?
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Acetaminophen
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Ibuprofen
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Aspirin
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Warfarin
A
Correct answer
Explanation
Acetaminophen, a widely used over-the-counter pain reliever, can cause liver damage, especially when taken in high doses or for prolonged periods.
Which of the following drugs is associated with an increased risk of developing drug-induced lupus?
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Hydralazine
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Procainamide
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Isoniazid
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All of the above
D
Correct answer
Explanation
Hydralazine, procainamide, and isoniazid are among the drugs that have been associated with an increased risk of developing drug-induced lupus, an autoimmune condition that can affect multiple organs.
Which of the following drugs is known to cause a condition called agranulocytosis?
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Clozapine
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Methotrexate
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Valproic acid
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All of the above
D
Correct answer
Explanation
Clozapine, methotrexate, and valproic acid are among the drugs that can cause agranulocytosis, a condition characterized by a severe decrease in the number of white blood cells.
Which of the following drugs is associated with an increased risk of developing photosensitivity?
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Tetracyclines
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Fluoroquinolones
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Sulfonamides
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All of the above
D
Correct answer
Explanation
Tetracyclines, fluoroquinolones, and sulfonamides are among the drugs that can cause photosensitivity, a condition in which the skin becomes more sensitive to sunlight and can develop sunburn more easily.
Which of the following drugs can cause a condition called ototoxicity?
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Aminoglycosides
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Loop diuretics
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Aspirin
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All of the above
D
Correct answer
Explanation
Aminoglycosides, loop diuretics, and aspirin are among the drugs that can cause ototoxicity, a condition characterized by damage to the inner ear that can lead to hearing loss and balance problems.
Which of the following drugs is associated with an increased risk of developing drug-induced lupus?
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Hydralazine
-
Procainamide
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Isoniazid
-
All of the above
D
Correct answer
Explanation
Hydralazine, procainamide, and isoniazid are among the drugs that have been associated with an increased risk of developing drug-induced lupus, an autoimmune condition that can affect multiple organs.
Which of the following drugs is known to cause a condition called agranulocytosis?
-
Clozapine
-
Methotrexate
-
Valproic acid
-
All of the above
D
Correct answer
Explanation
Clozapine, methotrexate, and valproic acid are among the drugs that can cause agranulocytosis, a condition characterized by a severe decrease in the number of white blood cells.
Which of the following is a sign of prescription drug abuse in the elderly?
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Taking more medication than prescribed
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Taking medication for longer than prescribed
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Mixing medications
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All of the above
D
Correct answer
Explanation
Taking more medication than prescribed, taking medication for longer than prescribed, and mixing medications are all signs of prescription drug abuse in the elderly. These behaviors can lead to serious health problems, including overdose and death.