Chemistry ยท Biology
Pharmacology and Therapeutics
1,643 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
What is the primary active compound in Sandalwood that gives it its cooling and anti-inflammatory properties?
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Santalol
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Alpha-santalol
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Beta-santalol
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Santalene
A
Correct answer
Explanation
Santalol, particularly alpha-santalol and beta-santalol, are the primary active compounds in Sandalwood that contribute to its cooling and anti-inflammatory properties.
What is the primary active compound in Licorice that gives it its anti-inflammatory and antiviral properties?
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Glycyrrhizin
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Glabridin
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Liquiritigenin
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Isoliquiritigenin
A
Correct answer
Explanation
Glycyrrhizin is the primary active compound in Licorice that contributes to its anti-inflammatory and antiviral properties, making it a valuable herb in Unani medicine for various health conditions.
What is the name of the new drug that has been shown to be effective in treating Alzheimer's disease?
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Aducanumab
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Lecanemab
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Donanemab
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Gantenerumab
A
Correct answer
Explanation
Aducanumab is a monoclonal antibody that has been shown to reduce amyloid plaques in the brain, which are a hallmark of Alzheimer's disease. In clinical trials, Aducanumab has been shown to slow the progression of cognitive decline in patients with Alzheimer's disease.
What is the most common type of drug interaction?
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Pharmacokinetic interactions
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Pharmacodynamic interactions
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Synergistic interactions
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Antagonistic interactions
A
Correct answer
Explanation
Pharmacokinetic interactions occur when one drug affects the absorption, distribution, metabolism, or excretion of another drug.
Which of the following drugs is known to interact with warfarin?
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Aspirin
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Ibuprofen
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Acetaminophen
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Vitamin K
D
Correct answer
Explanation
Vitamin K is a known antagonist of warfarin, which can reduce its anticoagulant effect.
Which of the following drugs is known to cause QT prolongation?
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Amiodarone
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Quinidine
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Sotalol
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All of the above
D
Correct answer
Explanation
Amiodarone, quinidine, and sotalol are all known to cause QT prolongation, which can increase the risk of torsades de pointes, a potentially fatal heart rhythm disorder.
Which of the following drugs is known to interact with lithium?
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Diuretics
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NSAIDs
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ACE inhibitors
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All of the above
D
Correct answer
Explanation
Diuretics, NSAIDs, and ACE inhibitors can all interact with lithium, increasing the risk of lithium toxicity.
Which of the following drugs is known to interact with alcohol?
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Acetaminophen
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Ibuprofen
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Aspirin
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All of the above
D
Correct answer
Explanation
Acetaminophen, ibuprofen, and aspirin can all interact with alcohol, increasing the risk of liver damage.
Which of the following drugs is known to interact with grapefruit juice?
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Statins
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Calcium channel blockers
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Beta-blockers
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All of the above
D
Correct answer
Explanation
Statins, calcium channel blockers, and beta-blockers can all interact with grapefruit juice, increasing the risk of adverse effects.
Which of the following drugs is known to cause hepatotoxicity?
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Acetaminophen
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Ibuprofen
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Aspirin
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All of the above
A
Correct answer
Explanation
Acetaminophen is the only drug listed that can cause hepatotoxicity, which is a liver condition.
Which of the following drugs is commonly associated with Stevens-Johnson Syndrome?
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Penicillin
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Sulfonamides
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Allopurinol
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Ibuprofen
B
Correct answer
Explanation
Sulfonamides are a group of antibiotics that can cause a severe skin reaction known as Stevens-Johnson Syndrome.
Which of the following drugs is commonly associated with hepatotoxicity?
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Acetaminophen
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Ibuprofen
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Aspirin
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Warfarin
A
Correct answer
Explanation
Acetaminophen, a widely used over-the-counter pain reliever, can cause liver damage, especially when taken in high doses or for prolonged periods.
Which of the following drugs is associated with an increased risk of developing drug-induced lupus?
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Hydralazine
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Procainamide
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Isoniazid
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All of the above
D
Correct answer
Explanation
Hydralazine, procainamide, and isoniazid are among the drugs that have been associated with an increased risk of developing drug-induced lupus, an autoimmune condition that can affect multiple organs.
Which of the following drugs is known to cause a condition called agranulocytosis?
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Clozapine
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Methotrexate
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Valproic acid
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All of the above
D
Correct answer
Explanation
Clozapine, methotrexate, and valproic acid are among the drugs that can cause agranulocytosis, a condition characterized by a severe decrease in the number of white blood cells.
Which of the following drugs is associated with an increased risk of developing photosensitivity?
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Tetracyclines
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Fluoroquinolones
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Sulfonamides
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All of the above
D
Correct answer
Explanation
Tetracyclines, fluoroquinolones, and sulfonamides are among the drugs that can cause photosensitivity, a condition in which the skin becomes more sensitive to sunlight and can develop sunburn more easily.