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Pharmacology and Therapeutics
1,643 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
What is the primary mechanism of action of NSAIDs in the treatment of pain?
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Binding to opioid receptors in the central nervous system
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Inhibition of prostaglandin synthesis
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Activation of the descending pain inhibitory system
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Blocking the reuptake of serotonin and norepinephrine
B
Correct answer
Explanation
NSAIDs inhibit the synthesis of prostaglandins, which are involved in the inflammatory process and the perception of pain.
What is the term for the use of a pain medication for a non-medical purpose?
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Tolerance
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Dependence
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Addiction
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Withdrawal
C
Correct answer
Explanation
Addiction is the term for the use of a pain medication for a non-medical purpose.
What is the term for the use of two or more pain medications at the same time?
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Polypharmacy
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Combination therapy
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Multimodal therapy
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All of the above
A
Correct answer
Explanation
Polypharmacy is the term for the use of two or more pain medications at the same time.
What is the first-line treatment for mild intermittent asthma in children?
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Inhaled corticosteroids
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Long-acting beta-agonists
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Leukotriene modifiers
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Oral corticosteroids
A
Correct answer
Explanation
Inhaled corticosteroids are the first-line treatment for mild intermittent asthma in children. They help to reduce inflammation in the airways.
What is the first-line treatment for a severe allergic reaction (anaphylaxis) in children?
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Epinephrine
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Antihistamines
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Corticosteroids
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Bronchodilators
A
Correct answer
Explanation
Epinephrine is the first-line treatment for a severe allergic reaction (anaphylaxis) in children. It is a life-saving medication that can help to open the airways and reduce swelling.
What is the first-line treatment for mild atopic dermatitis (eczema) in children?
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Moisturizers
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Topical corticosteroids
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Antihistamines
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Oral corticosteroids
A
Correct answer
Explanation
Moisturizers are the first-line treatment for mild atopic dermatitis (eczema) in children. They help to keep the skin hydrated and reduce itching.
What is the process by which the FDA approves new drugs for marketing in the United States?
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Investigational New Drug (IND) application
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New Drug Application (NDA)
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Abbreviated New Drug Application (ANDA)
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Biologics License Application (BLA)
B
Correct answer
Explanation
The process by which the FDA approves new drugs for marketing in the United States involves submitting a New Drug Application (NDA) to the FDA.
What is the generic drug approval pathway?
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Submitting an NDA to the FDA
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Submitting an ANDA to the FDA
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Submitting a BLA to the FDA
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Submitting a petition to the FDA
B
Correct answer
Explanation
The generic drug approval pathway involves submitting an Abbreviated New Drug Application (ANDA) to the FDA.
Which of the following is an example of a herbal medicine?
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Ginkgo biloba
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Ibuprofen
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Acetaminophen
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Aspirin
A
Correct answer
Explanation
Ginkgo biloba is a herbal medicine that is commonly used to improve memory and cognitive function.
Which of the following is an example of a homeopathic remedy?
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Arnica
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Ibuprofen
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Acetaminophen
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Aspirin
A
Correct answer
Explanation
Arnica is a homeopathic remedy that is commonly used to treat bruises, sprains, and muscle pain.
Which medication is commonly used to reduce stomach acid production in peptic ulcer treatment?
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Proton pump inhibitors (PPIs)
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Histamine-2 receptor antagonists (H2RAs)
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Antacids
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Sucralfate
A
Correct answer
Explanation
Proton pump inhibitors (PPIs) are a class of medications that effectively reduce stomach acid production, creating a favorable environment for ulcer healing.
Which medication is commonly used to protect the lining of the stomach and duodenum in peptic ulcer treatment?
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Proton pump inhibitors (PPIs)
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Histamine-2 receptor antagonists (H2RAs)
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Antacids
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Sucralfate
D
Correct answer
Explanation
Sucralfate is a medication that forms a protective coating over the ulcer, shielding it from stomach acid and promoting healing.
What is the name of the first drug approved by the FDA to treat cancer?
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Methotrexate
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Chlorambucil
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5-Fluorouracil
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Cyclophosphamide
A
Correct answer
Explanation
Methotrexate was the first drug approved by the FDA to treat cancer in 1953.
What is the name of the treatment that uses drugs to kill cancer cells?
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Chemotherapy
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Radiotherapy
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Surgery
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Immunotherapy
A
Correct answer
Explanation
Chemotherapy uses drugs to kill cancer cells.
What is the primary active compound found in turmeric that is responsible for its anti-inflammatory properties?
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Curcumin
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Gingerol
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Piperine
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Quercetin
A
Correct answer
Explanation
Curcumin is the primary active compound found in turmeric and is responsible for its anti-inflammatory properties.