Chemistry ยท Biology
Pharmacology and Therapeutics
1,699 Questions
Engage with critical pharmacology and therapeutics questions covering drug classifications and therapeutic mechanisms. Topics include chemical absorption, medication formulations, and pharmacogenomics. This collection is useful for students preparing for medical entrance, nursing, and science competitive examinations.
Chemical absorption routesDrug formulation typesMedication mechanismsEnzyme inhibitorsPharmacogenomic tests
Pharmacology and Therapeutics Questions
What is the antidote for digoxin overdose?
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Digibind
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Naloxone
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Activated charcoal
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N-acetylcysteine (NAC)
A
Correct answer
Explanation
Digibind is the antidote for digoxin overdose.
What is the antidote for iron overdose?
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Deferoxamine
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Naloxone
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Activated charcoal
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N-acetylcysteine (NAC)
A
Correct answer
Explanation
Deferoxamine is the antidote for iron overdose.
What is the antidote for lead poisoning?
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Chelation therapy
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Naloxone
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Activated charcoal
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N-acetylcysteine (NAC)
A
Correct answer
Explanation
Chelation therapy is the antidote for lead poisoning.
Which of the following is not a prohibited ingredient under Schedule H of the Drugs and Cosmetics Rules, 1945?
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Mercury
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Lead
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Arsenic
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Sodium Lauryl Sulfate
D
Correct answer
Explanation
Mercury, lead, and arsenic are prohibited ingredients under Schedule H of the Drugs and Cosmetics Rules, 1945 due to their potential toxicity and harmful effects on human health. Sodium Lauryl Sulfate, on the other hand, is a commonly used surfactant that is not prohibited.
Which of the following is NOT a common medication used for pain management in palliative care?
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Morphine
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Fentanyl
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Ibuprofen
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Acetaminophen
C
Correct answer
Explanation
Ibuprofen is not typically used for pain management in palliative care, as it is not as effective as opioids in managing severe pain.
What is the primary active compound in lemon balm that contributes to its calming and sedative properties?
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Citral
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Eugenol
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Piperine
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Thymol
A
Correct answer
Explanation
Citral is the primary active compound in lemon balm. It is responsible for the herb's calming and sedative properties.
Which of the following is a potential drug interaction with SSRIs?
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Warfarin
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Aspirin
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Ibuprofen
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Alcohol
A
Correct answer
Explanation
SSRIs can interact with warfarin, increasing the risk of bleeding due to inhibition of warfarin metabolism.
Which of the following is a potential drug interaction with pregabalin?
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Alcohol
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Opioids
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Benzodiazepines
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Anticonvulsants
A
Correct answer
Explanation
Pregabalin can interact with alcohol, potentiating the sedative effects of both substances.
Which of the following is a potential drug interaction with propranolol?
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Warfarin
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Aspirin
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Ibuprofen
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Alcohol
A
Correct answer
Explanation
Propranolol can interact with warfarin, increasing the risk of bleeding due to inhibition of warfarin metabolism.
Which of the following is NOT a route of drug administration?
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Oral
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Intravenous
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Transdermal
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Intramuscular
C
Correct answer
Explanation
Transdermal is not a route of drug administration, but rather a method of drug delivery through the skin.
The rate and extent of drug absorption is primarily determined by which of the following factors?
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Drug formulation
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Physicochemical properties of the drug
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Route of administration
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All of the above
D
Correct answer
Explanation
The rate and extent of drug absorption are influenced by a combination of drug formulation, physicochemical properties of the drug, and the route of administration.
The distribution of a drug in the body is influenced by which of the following factors?
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Protein binding
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Tissue perfusion
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Drug lipophilicity
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All of the above
D
Correct answer
Explanation
The distribution of a drug in the body is affected by protein binding, tissue perfusion, and drug lipophilicity.
Which of the following is NOT a mechanism of drug metabolism?
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Phase I reactions
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Phase II reactions
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Excretion
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Biotransformation
C
Correct answer
Explanation
Excretion is the process of eliminating drugs and their metabolites from the body, not a mechanism of drug metabolism.
The primary site of drug metabolism is the:
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Liver
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Kidneys
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Lungs
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Intestines
A
Correct answer
Explanation
The liver is the primary site of drug metabolism, where enzymes such as cytochrome P450 enzymes play a crucial role in metabolizing drugs.
The process of eliminating drugs and their metabolites from the body is known as:
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Absorption
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Distribution
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Metabolism
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Excretion
D
Correct answer
Explanation
Excretion is the process of eliminating drugs and their metabolites from the body, typically through the kidneys, liver, or intestines.