Biology
Molecular Genetics
851 Questions
Molecular genetics explores the mechanisms of genetic information transfer, including DNA replication, transcription, and translation. It is a core component of biology syllabi. These concepts frequently appear in general science sections of major competitive exams.
DNA replicationTranscription processTranslation processRNA typesCentral dogma
Molecular Genetics Questions
What is the central dogma of molecular biology?
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DNA makes RNA, RNA makes proteins
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RNA makes DNA, DNA makes proteins
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Proteins make DNA, DNA makes RNA
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Proteins make RNA, RNA makes DNA
A
Correct answer
Explanation
The central dogma of molecular biology states that DNA makes RNA, and RNA makes proteins. This flow of genetic information from DNA to RNA to proteins is essential for the synthesis of proteins, which are the building blocks of cells and perform various functions in living organisms.
Which of the following is NOT a type of RNA?
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Messenger RNA (mRNA)
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Transfer RNA (tRNA)
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Ribosomal RNA (rRNA)
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Deoxyribonucleic acid (DNA)
D
Correct answer
Explanation
Deoxyribonucleic acid (DNA) is not a type of RNA. RNA molecules are composed of ribose sugar, while DNA molecules are composed of deoxyribose sugar.
Which of the following is an example of a transcription factor?
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c-Jun
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c-Fos
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NF-κB
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All of the above
D
Correct answer
Explanation
c-Jun, c-Fos, and NF-κB are all examples of transcription factors that are involved in various cellular signaling pathways.
Which of the following is the primary genetic material in prokaryotic cells?
A
Correct answer
Explanation
Prokaryotic cells, such as bacteria and archaea, store their genetic information primarily in the form of DNA (deoxyribonucleic acid).
Which enzyme is responsible for synthesizing the RNA primers that are required for DNA replication?
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DNA polymerase
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Helicase
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Ligase
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Primase
D
Correct answer
Explanation
Primase is the enzyme that is responsible for synthesizing the RNA primers that are required for DNA replication. RNA primers are short pieces of RNA that are used to initiate DNA synthesis on the lagging strand. Primase synthesizes RNA primers in a 5' to 3' direction.
Which genetic material is passed from parents to offspring?
A
Correct answer
Explanation
DNA is the genetic material that is passed from parents to offspring, containing the instructions for an organism's development and characteristics.
What is the term for the process by which DNA is copied into RNA?
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Replication
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Transcription
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Translation
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Mutation
B
Correct answer
Explanation
Transcription is the process by which DNA is copied into RNA, creating a messenger molecule that carries the genetic information to the ribosomes for protein synthesis.
What is the term for the process by which RNA is used to synthesize proteins?
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Replication
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Transcription
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Translation
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Mutation
C
Correct answer
Explanation
Translation is the process by which RNA is used to synthesize proteins, involving the decoding of the genetic code and the assembly of amino acids into a polypeptide chain.
Which bioinformatics approach is used to analyze the structure and function of RNA molecules?
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Transcriptomics
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Proteomics
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Metabolomics
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Lipidomics
A
Correct answer
Explanation
Transcriptomics is the study of the structure and function of RNA molecules, including their expression levels, interactions, and role in cellular processes.
Which of the following is a type of nucleic acid?
A
Correct answer
Explanation
DNA is a type of nucleic acid that carries genetic information.
What is the term for the process by which cells regulate the expression of genes?
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Transcription
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Translation
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Gene regulation
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Protein synthesis
C
Correct answer
Explanation
The term for the process by which cells regulate the expression of genes is gene regulation.
What is the primary molecule that carries genetic information in cells?
A
Correct answer
Explanation
DNA (deoxyribonucleic acid) is the primary molecule that carries genetic information in cells. It is a double-stranded molecule composed of nucleotides, each consisting of a sugar molecule, a phosphate group, and a nitrogenous base.
What is the process by which DNA is copied during cell division?
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Replication
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Transcription
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Translation
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Mutation
A
Correct answer
Explanation
Replication is the process by which DNA is copied during cell division. During replication, the DNA double helix unwinds and each strand serves as a template for the synthesis of a new complementary strand. This results in the formation of two identical copies of the original DNA molecule.
What is the process by which the genetic information in DNA is used to direct the synthesis of proteins?
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Replication
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Transcription
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Translation
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Mutation
B
Correct answer
Explanation
Transcription is the process by which the genetic information in DNA is used to direct the synthesis of proteins. During transcription, a specific region of DNA is copied into a complementary RNA molecule. This RNA molecule, known as messenger RNA (mRNA), carries the genetic information to the ribosomes, where it is used to direct the synthesis of proteins.
What is the process by which the genetic information in mRNA is used to direct the synthesis of proteins?
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Replication
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Transcription
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Translation
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Mutation
C
Correct answer
Explanation
Translation is the process by which the genetic information in mRNA is used to direct the synthesis of proteins. During translation, the mRNA molecule is read by ribosomes, which use the genetic code to determine the sequence of amino acids in the protein. The amino acids are then linked together to form a polypeptide chain, which folds into a specific three-dimensional structure to form the functional protein.