Biology

Human Genetics and Disorders

882 Questions

Human Genetics and Disorders covers the inheritance patterns, genetic mutations, and molecular basis of hereditary diseases. Topics include sex-linked traits, cancer genetics, and metabolic disorders. This section tests knowledge critical for biology exams and general science papers.

Genetic mutationsInherited disordersCancer geneticsGenetic testingMendelian inheritance

Human Genetics and Disorders Questions

Multiple choice

What do you mean by hypostatic gene?

  1. A gene in which mutation occurs

  2. A gene whose phenotype remains unaltered

  3. A gene whose genotype is altered or suppressed

  4. A gene whose phenotype is altered or suppressed

  5. None of these
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

A hypostatic gene is a gene whose phenotype is altered or suppressed.

Multiple choice

Which complement factor is associated with C1q deficiency which occurs due to formation of C1q antibodies?

  1. Partial lipodystrophy

  2. Type II membranoproliferative glomerulonephritis (MPGN II)

  3. Hypocomplementemic urticarial vasculitis syndrome (HUVS)

  4. Systemic lupus erythematosus (SLE)
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Hypocomplementemic urticarial vasculitis syndrome (HUVS) (also called SLE-related syndrome or chronic hypocomplementemic cutaneous vasculitis) is a disorder associated with anti-C1q antibodies that leads to classical pathway activation and chronic decreases in C1, C2, C4 and C3 levels.

Multiple choice

'Infantile amourotic idiocy' is caused due to

  1. a recessive allele in homozygous condition

  2. a dominant allele in homozygous condition

  3. Both (A) and (B)

  4. None of these
Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

In human beings a few lethal genes are known which are associated with fatal 'Infantile amourotic idiocy' disease, and is caused by recessive allele in homozygous condition.

Multiple choice

Albinism is a

  1. deficiency disease

  2. hereditary disease

  3. degenerative disease

  4. sex-linked disease
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Albinism is an inherited (hereditary) genetic condition caused by mutations in genes involved in melanin production. It is not a deficiency disease (caused by lack of nutrients), degenerative disease (progressive deterioration), or exclusively sex-linked (though some forms can be X-linked).