Human Genetics and Disorders

Hypocomplementemic urticarial vasculitis syndrome (HUVS) (also called SLE-related syndrome or chronic hypocomplementemic cutaneous vasculitis) is a disorder associated with anti-C1q antibodies that leads to classical pathway activation and chronic decreases in C1, C2, C4 and C3 levels.

Galactosemia is an inborn error of metabolism inherited as an autosomal recessive trait.

Tay-Sachï؟½s is an inherited disease. It results when a child receives two defective genes, one from each parent.

In human beings a few lethal genes are known which are associated with fatal 'Infantile amourotic idiocy' disease, and is caused by recessive allele in homozygous condition.

G0/G1 switch gene 2 (G0s2) represents a novel regulator of adipogenesis.

 Edward's syndrome is an abnormality leading to mental deficiency. It is caused by trisomy of chromosome number 18.

Albinism is an inherited (hereditary) genetic condition caused by mutations in genes involved in melanin production. It is not a deficiency disease (caused by lack of nutrients), degenerative disease (progressive deterioration), or exclusively sex-linked (though some forms can be X-linked).

In sickle cell anemia, individuals with the homozygous recessive state (HbS/HbS) suffer severe, often fatal, medical complications due to the malformation of red blood cells. Heterozygotes (carriers) generally exhibit normal health with resistance to malaria.

The scientific name for modern humans is Homo sapiens, following the binomial nomenclature system. In this name, 'Homo' represents the genus and 'sapiens' represents the species. Other options like Rana tigrina and Labeo rohita refer to a frog and a fish, respectively.

Correct option is (1). 

Androgen insensitivity syndrome is a congenital genetic disorder causing genetic males to behave like females, due to the inability to utilise androgens.

Yes, it is the correct answer.

Reiter's syndrome is a triad of symptoms that include conjunctivitis, polyarthritis and genital inflammation. The disease is associated with HLA-B27.

Inherited causes now account for 50% of all cases of severe sensorineural hearing impairment; 80% are due to single-gene autosomal recessive disorders and 15% to autosomal dominant disorders.

Mismatching of Rh factor causes Erythroblastosis foetalis or Hemolytic Disease of the Newborn (HDN). This fetal disease ranges from mild to very severe, and fetal death from heart failure (hydrops fetalis) can occur. Mismatching of Rh factor causes Erythroblastosis foetalis or Hemolytic Disease of the Newborn (HDN).