Multiple choice general knowledge science & technology Which gland in the human body is called the master gland? Pancreas Thyroid Pituitary Spleen Reveal answer Fill a bubble to check yourself C Correct answer Explanation The pituitary gland is called the 'master gland' because it controls other endocrine glands through hormones like TSH, ACTH, FSH, and LH. The pancreas regulates blood sugar, thyroid controls metabolism, and spleen is part of the immune system.