Multiple choice

The deletion of the POMC gene in Retrievers means?

  1. Decrease in Adiposity (Weight gain)

  2. Increase in Adiposity (Weight gain)

Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

The pro-opiomelanocortin (POMC) gene deletion, which is common in Labrador Retrievers and Flat-Coated Retrievers, disrupts the neural pathways that signal satiety. This genetic mutation leads to increased food-seeking behavior, a higher appetite, and a significant predisposition to increased adiposity and weight gain.