Multiple choice

Which of the following statements is/are TRUE about JUXTACRINE signaling? I. The ligand and the receptor engage in reciprocal signaling. II. Both the ligand and the receptor are membrane associated proteins. III. The ligand gets proteolytically cleaved after binding to the receptor.

  1. I only

  2. II only

  3. III only

  4. I, II and III
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Juxtacrine signaling requires both the signaling cell's ligand and the responding cell's receptor to be membrane-associated proteins, as direct cell-to-cell contact is necessary.

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