Multiple choice

Down syndrome is caused due to which of the following?

  1. Increase in number of chromosomes in 21st pair autosome

  2. Decrease in number of chromosomes in 21st pair autosome

  3. Increase in number of chromosomes in 18th pair autosome

  4. Decrease in number of chromosomes in 18th pair autosome

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A Correct answer
Explanation

Down syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. It is typically associated with physical growth delays, characteristic facial features and mild to moderate intellectual disability.