Multiple choice

Which among the following indicates the autoantigen selection of responding B-cells during an infection in the body?

  1. Germ line configuration of the antibody

  2. High affinity antibody

  3. Expression of a public idiotype

  4. A monoclonal antibody response

  5. A response to many different autoantigens
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

The mutation of the antibody variable region genes in B-cells in the germinal center produces a range of antibody affinities, and those B-cells bearing higher affinity antibody will be favourably selected for further stimulation by the antigen.

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