Multiple choice What is meant by medullary interstitium? It is the medullary extension of the renal cortex in between the renal pyramids. It is the functional space in the kidney beneath the individual fibres. It is a dense fibrous connective tissue sheath which surrounds the kidney. It is the inner layer of the kidney which contains some portions of the renal tubules and most of the collecting duct tubules of the kidney. Reveal answer Fill a bubble to check yourself B Correct answer Explanation The medullary interstitium is the functional space in the kidney beneath the individual filters (glomeruli), which are rich in blood vessels. The interstitium absorbs fluid recovered from urine.