Multiple choice

Which of the following statements is/are correct about anti-thrombin aptamers?

P. These are G-quadruplex-bearing polynucleotides. Q. They show poor affinity and specificity against thrombin. R. They are bound to the exosite I of thrombin majorly via their two TT loops through polar and hydrophobic interactions.

  1. Only P

  2. Only Q

  3. Only R

  4. Only P and Q

  5. Only Q and R

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

This option is correct. They are bound to the exosite I of thrombin majorly via their two TT loops through polar and hydrophobic interactions.