Multiple choice

Match the entries in Group - I with those in Group - II.

 
Group - I
Group - II
P. PSI-BLAST 1. Iteratively searches one or more protein databases for sequences similar to one or more protein query sequences.
Q. PHI-BLAST 2. Searches for proteins that contain a pattern specified by the user AND are similar to the query sequence in the vicinity of the pattern.
R. blastp 3. Used for both identifying a query amino acid sequence and for finding similar sequences in protein databases.

  1. P - 1, Q - 2, R - 3

  2. P - 2, Q - 3, R - 1

  3. P - 2, Q - 1, R - 3

  4. P - 3, Q - 1, R - 2

  5. P - 3, Q - 2, R - 1

Reveal answer Fill a bubble to check yourself
A Correct answer
Explanation

Position-Specific Iterated BLAST (PSIBLAST) iteratively searches one or more protein databases for sequences similar to one or more protein query sequences. PSIBLAST is similar to BLAST except that it uses position-specific scoring matrices derived during the search. Pattern-Hit Initiated BLAST (PHI-BLAST) is designed to search for proteins that contain a pattern specified by the user AND are similar to the query sequence in the vicinity of the pattern. This dual requirement is intended to reduce the number of database hits that contain the pattern, but are likely to have no true homology to the query. Standard protein-protein BLAST (blastp) is used for both identifying a query amino acid sequence and for finding similar sequences in protein databases. Like other BLAST programs, blastp is designed to find local regions of similarity. When sequence similarity spans the whole sequence, blastp will also report a global alignment, which is the preferred result for protein identification purposes.