Fibrin (also called Factor Ia) is a fibrous protein, involved in the clotting of blood, and is non-globular. It is a fibrillar protein, that is polymerised to form a mesh, that forms a hemostatic plug or clot (in conjunction with platelets) over a wound site. Fibrin is involved in the following biological processes: signal transduction, blood coagulation, platelet activation and protein polymerization.