Multiple choice During blood clotting, which of the following occurs? Fibrin is converted to fibrinogen by thrombin Fibrinogen is converted to fibrin by thrombin Fibrinogen is converted to fibrin by prothrombin Fibrin is converted to fibrinogen by prothrombin Reveal answer Fill a bubble to check yourself B Correct answer Explanation Thrombin is an active enzyme that catalyzes the conversion of the soluble plasma protein fibrinogen into insoluble fibrin strands. These fibrin strands form a mesh that traps blood cells to form a clot.