Multiple choice

Specific immunity to M. tuberculosis in mice, can be transferred to naive histocompatible recipients by which of the following?

  1. B-cells

  2. T-cells

  3. Macrophages

  4. Neutrophils

  5. IgG
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

T-cells are important for immunity to M. tuberculosis through the provision of Th1 cytokines,  such as IFN-gamma to activate macrophages containing the bacilli and perhaps also the participation of cytotoxic T-cells. The latter may kill macrophages,  which cannot be rescued by cytokines thereby releasing the bacteria to be taken up by fresh young macrophages. They can be activated to become killers.

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