Multiple choice

Which of the following statements is not true for viral antigen?

  1. ELISAs provide a valuable tool in the detection and diagnosis of virus infection.

  2. Recombinant viral antigens contain part of viral sequence.

  3. Recombinant viral protein usually contains a fusion protein.

  4. Recombinant Viral proteins are expressed in bacteria, yeast, mammalian cells etc.

  5. Serum antibodies form a first layer of protection of the host from viral infection.

Reveal answer Fill a bubble to check yourself
E Correct answer
Explanation

Antibody-based immune responses form a first layer of protection of the host from viral infection; however, in many cases a vigorous cellular immune response mediated by T-cells and NK-cells is required for effective viral clearance. When cellular immunity is unable to clear the virus, the infection can become chronic, and serum antibodies to the viral pathogen are used as first indicator for the diagnosis of the disease.