Multiple choice

In Burkitt's lymphoma, a vaccine against which of the following viruses might prove useful?

  1. Epstein-Barr virus

  2. Marek's disease virus

  3. Human papilloma virus

  4. HTLV-1

  5. MMTV
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A Correct answer
Explanation

In human Burkitt's lymphoma, work is in progress to develop a vaccine to exploit the ability of cytotoxic T-cells to target EBV-related antigens on the cells of all Burkitt's tumors. It may be an advantage to treat the patients at the same time with cytokines to upregulate the expression of ICAM-1, LFA-3 and possibly of the virus itself.

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