Multiple choice

Which of the following is not true about thiopentone?

  1. NaCO3 is a preservative

  2. Contraindicated in Porphyrias

  3. Agent of choice in shock

  4. Cerebroprotective
Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Thiopentone is contraindicated in shock states because it causes significant cardiovascular depression including myocardial depression and vasodilation, which can worsen hypotension. It is indeed contraindicated in porphyrias due to induction of ALA synthase. Thiopentone has cerebroprotective effects by reducing cerebral metabolic rate and intracranial pressure. While sodium carbonate/bicarbonate is added to the formulation, it functions as a buffer/stabilizer rather than primarily as a preservative.

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