Multiple choice

In a patient with muscle weakness and fever due to a mitochondrial myopathy, ATP synthesis is reduced but electron transport is normal. The inner mitochondrial membrane of the patient's muscle might show

  1. absence of cristae

  2. defective calcium pump

  3. missing porin

  4. open anion channels

  5. loss of F1 particles
Reveal answer Fill a bubble to check yourself
D Correct answer
Explanation

Voltage-dependent anion channels are a class of porin ion channel located on the outer mitochondrial membrane. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV.

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