Multiple choice

The structural abnormalities of chromosome associated with Wolf-Hirschhorn syndrome is

  1. deletions

  2. duplications

  3. the Robertsonian translocation

  4. isochromosome

  5. inversions
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A Correct answer
Explanation

Here a portion of the chromosome is missing or deleted. Known disorders in humans include Wolf-Hirschhorn syndrome, which is caused by partial deletion of the short arm of chromosome 4; and Jacobsen syndrome, also called the terminal 11q deletion disorder.

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