Multiple choice

Eukaryotic DNA replication is a conserved mechanism. Which of the following statements does NOT characterise the DNA replication?

  1. Each Okazaki fragment is preceded by an RNA dimer.

  2. The lagging strand usually contains longer stretches of single-stranded DNA.

  3. Okazaki fragments are formed on the lagging strand.

  4. Two replicative polymerases synthesise DNA in opposite orientations.

  5. Duplex DNA is always antiparallel.

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A Correct answer
Explanation

Each Okazaki fragment is preceded by an RNA primer, which is displaced by the procession of the next Okazaki fragment during synthesis.