Multiple choice

Which among the following statements regarding the Okazaki fragments is incorrect?

  1. Okazaki fragments are formed on the lagging template strand during DNA replication.

  2. They are separated by ~10-nucleotide RNA primers and are unligated until RNA primers are removed.

  3. On the leading strand DNA replication proceeds continuously along the DNA molecule.

  4. DNA is synthesised from 3' to 5' end.

  5. There are two pathways that have been proposed to process Okazaki fragments.
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D Correct answer
Explanation

DNA is synthesised from 5' to 3', thus when copying the 3' to 5' strand, replication is continuous. Phosphodiester links form between the 3' to 5' and nucleotides can be added with the aid of the enzyme DNA polymerase for the continuous leading strand.

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