Multiple choice

Which among the following statements regarding baculoviruses is incorrect?

  1. Baculoviruses are lytic viruses, primarily pathogenic for insects.

  2. Non-genetically modified wild type baculoviruses are not capable of infecting vertebrate cells.

  3. Baculovirus is insensitive to human complement.

  4. The budded form of the virus routinely used in research is non-infectious for the insect host.

  5. Polyhedrin negative baculovirus expression system is susceptible to desiccation and UV light.

Reveal answer Fill a bubble to check yourself
C Correct answer
Explanation

Transmission of baculovirus is through direct contact with the infective virus/vector. Baculovirus is highly sensitive to human complement and therefore, should an exposure occur, rapid inactivation of the virus is anticipated.