Multiple choice

Type 1 T helper (Th1) cells produce interferon-gamma, interleukin (IL)-2, and tumour necrosis factor (TNF)-beta, which activate macrophages at the time of infections. Th1 cells are of major importance in defence against which of the following protozoans?

  1. Trypanosoma brucei

  2. Leishmania donovani

  3. Malarial merozoites

  4. Malarial sporozoites

  5. Trichinella spiralis
Reveal answer Fill a bubble to check yourself
B Correct answer
Explanation

Th1 cells produce cytokines which activate the killing macrophages. Where Th2 cells predominate, antibodies are produced and the individual responds poorly to the infection.

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