Multiple choice

Which of the following genetic disorders is monosomic?

  1. Dermoid tumors of the ovary

  2. Turner syndrome

  3. Hydatidiform mole

  4. Klinefelter syndrome

  5. Fragile X syndrome
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B Correct answer
Explanation

A monosomic disorder results when a chromosome pair fails to separate during either meiosis 1 or 2, a process known as nondisjunction. Nondisjunction can result in monosomy or trisomy. Turner syndrome occurs when part or all of the second sex chromosome is absent, resulting in a 45X karyotype.

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